Indication
Leptic ODT is indicated for the treatment of
• Seizure disorder
• Panic disorder
• Insomnia
Dosage and Administration
| Indication | Patient Category | Recommended dose | ||
| Seizure Disorders | Adults | Initial dosage | Increment dosage | Maximum dosage |
| The initial dose for adults with seizure disorders should not exceed 1.5 mg/day divided into three doses. | Dosage may be increased in increments of 0.5 to 1 mg every 3 days until seizures are adequately controlled or until side effects preclude any further increase. | Maximum recommended daily dose is 20 mg. | ||
| Pediatric Patients | The initial dose for infants and children (up to 10 years of age or 30 kg of body weight) should be between 0.01 and 0.03 mg/kg/day but not to exceed 0.05 mg/kg/day given in two or three divided doses. | Dosage should be increased by no more than 0.25 to 0.5 mg every third day until a daily maintenance dose of 0.1 to 0.2 mg/kg of body weight has been reached, unless seizures are controlled or side effects preclude further increase. | 0.05 mg/kg/day | |
| Geriatric Patients | In general, elderly patients should be started on low doses of Clonazepam and observed closely. | - | 20 mg/day | |
| Panic Disorder | Adults | The initial dose for adults with panic disorder is 0.25 mg twice daily. | An increase to the target dose for most patients of 1 mg/day may be made after 3 days. The recommended dose of 1 mg/day is based on the results from a fixed dose study in which the optimal effect was seen at 1 mg/day. | 20 mg/day |
| Pediatric Patients | There is no clinical trial experience with Clonazepam in panic disorder patients under 18 years of age | - | - | |
| Geriatric Patients | In general, elderly patients should be started on low doses of Clonazepam and observed closely. | - | 20 mg/day | |
| Insomnia | Adults | Doses of 0.25 to 0.5 mg PO at bedtime have been suggested. | - | 20 mg/day |
| Geriatric Adults | Doses of 0.25 to 0.5 mg PO at bedtime have been suggested for younger adults. | - | 20 mg/day |
Composition
Leptic 0.5: Each box contains 5x10 & 10x10 tablets in Alu-PVC/PVDC blister strips.
Leptic 1: Each box contains 3x10 & 5x10 tablets in Alu-PVC/PVDC blister strips.
Leptic 2: Each box contains 3x10 & 5x10 tablets in Alu-PVC/PVDC blister strips.
Leptic ODT 0.25: Each box contains 3x10 orally disintegrating tablets in Alu-Alu blister strips.
Leptic ODT 0.5: Each box contains 3x10 orally disintegrating tablets in Alu-Alu blister strips.